University of Missouri-Kansas City, School of Medicine, 2411 Holmes St, Kansas City, MO 64108, USA.
Pediatr Radiol. 2011 Apr;41(4):483-7. doi: 10.1007/s00247-010-1889-y. Epub 2010 Nov 16.
Isolated borderline low conus medullaris is a frequent finding on screening lumbar sonography of unknown significance that often prompts further imaging and clinical follow-up.
To determine the clinical outcome and utility of follow-up neuroimaging in infants with isolated borderline low conus on lumbar sonography.
We reviewed 748 consecutive spinal sonograms identifying infants with conus terminating between L2-L3 disc space and mid-L3 level without other findings of tethered cord. We excluded infants with conditions associated with developmental delay and those who passed away, and compared the age of gross motor milestone achievement to normal ranges. Follow-up imaging was reviewed.
Isolated borderline low conus was found in 90 of 748 infants (12%) on sonography. Seventy of those infants met inclusion criteria. Follow-up imaging in 11 children (10 MRI, 1 sonogram), showed change in conus position to "normal" level in 10, no change in 1, and no new findings within lumbar spine. Clinical follow-up was available in 50 of 70 (71%) children meeting inclusion criteria, with normal motor milestones met in all 50 children.
Isolated borderline low conus is a common finding in infants who meet normal developmental milestones suggesting that follow-up evaluation has little utility and is likely unwarranted.
孤立性边界低位圆锥是腰骶部超声筛查中常见的无明显意义的发现,常提示进一步进行影像学检查和临床随访。
确定孤立性边界低位圆锥在腰骶部超声检查中的婴儿的临床结局和神经影像学随访的应用价值。
我们回顾了 748 例连续的脊髓超声检查,发现圆锥终止于 L2-L3 椎间盘水平和中 L3 水平之间,无其他脊髓栓系的表现。我们排除了与发育迟缓相关的婴儿和死亡的婴儿,并将粗大运动里程碑的年龄与正常范围进行了比较。对随访的影像学检查进行了回顾。
在 748 例婴儿的超声检查中,90 例(12%)发现孤立性边界低位圆锥。其中 70 例符合纳入标准。11 例患儿(10 例 MRI,1 例超声)的随访影像学检查显示,圆锥位置改变为“正常”水平的有 10 例,无改变的有 1 例,腰椎内无新发现。符合纳入标准的 70 例患儿中有 50 例获得了临床随访,所有 50 例患儿的运动里程碑均正常。
孤立性边界低位圆锥在符合正常发育里程碑的婴儿中较为常见,提示随访评估的作用有限,可能是不必要的。