用三氟拉嗪对天然及阳离子交换细菌孢子进行化学萌发处理。
Chemical germination of native and cation-exchanged bacterial spores with trifluoperazine.
作者信息
Sacks L E
机构信息
Western Regional Research Center, U.S. Department of Agriculture, Albany, California 94706.
出版信息
Appl Environ Microbiol. 1990 Apr;56(4):1185-7. doi: 10.1128/aem.56.4.1185-1187.1990.
Abstract
The calmodulin antagonist trifluoperazine and its analog chlorpromazine, both amphipaths, induced chemical germination of spores of various species, as do many surfactants. Cation load can greatly influence this response. Calmodulin antagonism does not seem to be involved. A new fluorometric assay for dipicolinic acid based on the fluorescence of the dipicolinic acid chelate of Tb3+ was found to be simple and sensitive.
摘要
钙调蛋白拮抗剂三氟拉嗪及其类似物氯丙嗪均为两亲性物质，与许多表面活性剂一样，能诱导多种物种的孢子进行化学萌发。阳离子负载可极大地影响这种反应。似乎与钙调蛋白拮抗作用无关。基于Tb3 +的二吡啶甲酸螯合物荧光建立的一种新的二吡啶甲酸荧光测定法，被发现既简单又灵敏。
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