Roy Suman Kumar, Bhattacharjee Anup Kumar, Sinha Neloy
MGM Medical College, Kishanganj 855107,
J Indian Med Assoc. 2010 Apr;108(4):243-6.
A cross-sectional study was carried out at Naihati municipal area in West Bengal to study the prevalence and some epidemiological factors in transmission of leprosy. Side by side, the validity of WHO operational classification was also tested by using slit skin smear examination as gold standard. A group of trained paramedical workers, supervised by epidemiologist conducted house to house survey work. Experienced dermatologist and neurologist examined suspected cases. Overall prevalence of leprosy were 9.9 per 10000, of which 53% were new cases. Epidemiologically manual workers, living in slums and unhygienic surroundings had significantly higher risk of developing leprosy. Sensitivity and specificity of WHO operational classification (> 5 skin lesion= MB) was found to be quite high (sensitivity 85.9% and specificity 83.3%) in this study. However addition of > 2 nerve lesions to this criteria increase sensitivity to 90.1% without much affecting the specificity (79.8%).
在西孟加拉邦奈哈提市辖区开展了一项横断面研究,以研究麻风病的患病率及一些传播的流行病学因素。同时,还以皮肤涂片检查作为金标准,对世界卫生组织(WHO)的操作分类的有效性进行了测试。一组由流行病学家监督的经过培训的辅助医务人员挨家挨户进行调查工作。经验丰富的皮肤科医生和神经科医生对疑似病例进行检查。麻风病的总体患病率为每10000人中有9.9例,其中53%为新病例。从流行病学角度看,体力劳动者、生活在贫民窟和不卫生环境中的人患麻风病的风险显著更高。在本研究中,WHO操作分类(>5处皮肤损害=多菌型)的敏感性和特异性相当高(敏感性85.9%,特异性83.3%)。然而,在此标准中增加>2处神经损害会使敏感性提高到90.1%,而对特异性影响不大(79.8%)。