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一项关于非手术牙周治疗对 2 型糖尿病患者影响的随机对照试验。第一部分:对牙周状况和血糖控制的影响。

A randomized, controlled trial on the effect of non-surgical periodontal therapy in patients with type 2 diabetes. Part I: effect on periodontal status and glycaemic control.

机构信息

Department of Periodontology, School of Dentistry, University of Athens, Athens, Greece.

出版信息

J Clin Periodontol. 2011 Feb;38(2):142-7. doi: 10.1111/j.1600-051X.2010.01652.x. Epub 2010 Nov 29.

Abstract

AIM

the purpose of the present study was to assess the effect of non-surgical periodontal therapy on glycaemic control of type 2 diabetes patients with moderate-to-severe periodontitis.

MATERIALS AND METHODS

this was a randomized, controlled clinical trial of patients with type 2 diabetes. A total of 60 patients with moderate-to-severe periodontal disease were assigned to either a periodontal treatment arm, consisting of scaling and root planing (intervention group [IG]), or a delayed treatment arm that received periodontal care after 6 months (control group [CG]). Periodontal parameters and glycosylated haemoglobin (A1C) were evaluated at 1, 3 and 6 months.

RESULTS

all periodontal parameters improved significantly in the IG. A1C levels decreased statistically significantly more in the IG versus the CG (0.72%versus 0.13%; p<0.01) independently of other confounders.

CONCLUSIONS

this study provides evidence that periodontal treatment contributes to improved glycaemic control in type 2 diabetes mellitus patients. Larger controlled trials are needed to confirm if this finding is generalizable to other populations of patients with type 2 diabetes.

摘要

目的

本研究旨在评估非手术性牙周治疗对 2 型糖尿病伴中重度牙周炎患者血糖控制的影响。

材料与方法

这是一项针对 2 型糖尿病患者的随机对照临床试验。共有 60 名中重度牙周病患者被分为牙周治疗组(刮治和根面平整,干预组 [IG])或延迟治疗组(在 6 个月后接受牙周治疗,对照组 [CG])。在 1、3 和 6 个月时评估牙周参数和糖化血红蛋白(A1C)。

结果

IG 中所有牙周参数均显著改善。IG 组的 A1C 水平比 CG 组显著降低(0.72%比 0.13%;p<0.01),与其他混杂因素无关。

结论

本研究提供了证据表明牙周治疗有助于改善 2 型糖尿病患者的血糖控制。需要更大规模的对照试验来证实这一发现是否适用于其他 2 型糖尿病患者群体。

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