Dhanani Sonny, Barrowman Nick J, Ward Roxanne E, Murto Kimmo T
Department of Pediatric Critical Care, Children's Hospital of Eastern Ontario, ON, Canada.
Paediatr Anaesth. 2011 Aug;21(8):858-64. doi: 10.1111/j.1460-9592.2010.03480.x. Epub 2010 Dec 15.
Accurate and reliable evaluation of cardiac index (CI) in critically ill pediatric patients can optimize their management. Although validated, noninvasive ultrasound measurement techniques have been previously shown to be unreliable because of observer variability.
To confirm intra- and inter-observer reliability when using the noninvasive USCOM(®) in healthy anesthetized children.
Prospective observational study at the Children's Hospital of Eastern Ontario, Ottawa, included newborns to 12 years of age undergoing elective surgery or magnetic resonance imaging. The USCOM(®) was used to assess CI via aortic flow with a trans-sternal approach. Two trained observers were responsible for taking two measurements of CI each at steady state in randomized succession after stable depth of anesthesia was achieved.
Fifty-nine patients were included. Forty-seven (80%) were between 3 and 7 years old, with 57% male. The mean difference ± sd for repeat CI measurements by each of two observers was 0.11 ± 0.47 and 0.05 ± 0.65 l·min(-1) ·m(-2) , respectively. Intra-observer reliability for these repeat measurements by each observer determined by Lin's concordance correlation coefficient was 0.92 and 0.85, respectively. The mean difference ± sd between observers was 0.16 ± 0.59 l·min(-1) ·m(-2) , and Lin's concordance correlation coefficient was 0.87. The two observers subjectively rated measurements as 'Difficult' or 'Very difficult' only 14% (16/118) and 3% (4/118) of the time, respectively. No adverse events were reported.
This study confirms that the USCOM(®) is relatively easy to use and reliable in healthy children when operated by trained users.
准确可靠地评估危重症儿科患者的心脏指数(CI)有助于优化其治疗管理。尽管非侵入性超声测量技术已经过验证,但先前研究表明,由于观察者之间的差异,该技术并不可靠。
验证在健康麻醉儿童中使用非侵入性USCOM(®)时观察者内和观察者间的可靠性。
在渥太华东安大略儿童医院进行的前瞻性观察性研究,纳入了接受择期手术或磁共振成像的新生儿至12岁儿童。使用USCOM(®)经胸骨途径通过主动脉血流评估CI。两名经过培训的观察者负责在麻醉深度稳定后,以随机顺序在稳态下各进行两次CI测量。
共纳入59例患者。47例(80%)年龄在3至7岁之间,男性占57%。两名观察者各自重复测量CI的平均差值±标准差分别为0.11±0.47和0.05±0.65 l·min(-1)·m(-2)。通过林氏一致性相关系数确定,每名观察者这些重复测量的观察者内可靠性分别为0.92和0.85。观察者之间的平均差值±标准差为0.16±0.59 l·min(-1)·m(-2),林氏一致性相关系数为0.87。两名观察者分别仅在14%(16/118)和3%(4/118)的测量中主观评定为“困难”或“非常困难”。未报告不良事件。
本研究证实,由经过培训的人员操作时,USCOM(®)在健康儿童中相对易于使用且可靠。