Urology department, Urology & Nephrology Center, Mansoura University, Mansoura, Egypt.
BJU Int. 2011 Sep;108(5):750-4. doi: 10.1111/j.1464-410X.2010.09942.x. Epub 2010 Dec 16.
• To study long-term results of percutaneous nephrolithotomy (PNL) for treatment of staghorn stones.
• The records of patients who underwent PNL for staghorn stones between January 1998 and January 2008 were retrospectively reviewed. • Patients who completed follow-up for one year or more were included. Follow-up with KUB and renal ultrasonography were performed every 3-6 months. • Renal radioisotopic scan was performed for patients who had already undergone this study before doing PNL.
• The study included 122 patients (69 male and 53 female) with mean age 47.6 ± 14.5 years (5-74). They underwent 126 PNL. • Perioperative complications were encountered in 28 procedures (22%). The mean period of follow-up was 3.5 ± 2.3 years (1-11.3). Among 71 stone-free kidneys, 18 (25%) developed stone recurrence. Of 55 kidneys with residuals at the start of follow-up, 36 (65%) showed growth of these residuals. • Preoperative and postoperative renograms were performed for 71 patients. • At the last follow-up, differential GFR was stable in 53 (74.5%), improved in 12 (17%) and deteriorated in 6 (8.5%). Among patients with deteriorated renal function, 3 had undergone embolization to control severe bleeding, one developed secondary UPJO, and one had recurrent stone obstructing the kidney.
• Long-term functional results of PNL for staghorn stones are satisfactory as 91.5% of kidneys showed stable or improved GFR. Long-term follow-up is mandatory especially for patients with residual stones.
• 研究经皮肾镜取石术(PNL)治疗鹿角结石的长期疗效。
• 回顾性分析 1998 年 1 月至 2008 年 1 月期间接受 PNL 治疗鹿角结石的患者病历。• 纳入完成 1 年以上随访的患者。每 3-6 个月进行 KUB 和肾脏超声检查随访。• 对已行 PNL 术前肾放射性核素扫描的患者进行该检查。
• 研究共纳入 122 例患者(69 例男性,53 例女性),平均年龄 47.6±14.5 岁(5-74 岁)。共进行 126 次 PNL。• 28 例(22%)发生围手术期并发症。平均随访时间为 3.5±2.3 年(1-11.3 年)。在 71 例结石清除的肾脏中,18 例(25%)结石复发。在开始随访时有残余结石的 55 例肾脏中,36 例(65%)残余结石增大。• 71 例患者进行了术前和术后肾图检查。• 在最后一次随访时,53 例(74.5%)患者的肾小球滤过率稳定,12 例(17%)改善,6 例(8.5%)恶化。在肾功能恶化的患者中,3 例因严重出血行栓塞治疗,1 例发生继发性肾盂输尿管连接部梗阻,1 例因结石复发导致肾脏梗阻。
• PNL 治疗鹿角结石的长期功能结果令人满意,91.5%的肾脏肾小球滤过率稳定或改善。必须进行长期随访,特别是对有残余结石的患者。