Oncofertility Consortium, Northwestern University, Chicago, IL, 60611, USA.
J Cancer Surviv. 2011 Jun;5(2):152-7. doi: 10.1007/s11764-010-0166-2. Epub 2010 Dec 31.
Recent improvements in cancer detection, treatment, and technology have increased survivorship rates. These same life-saving treatments, however, can lead to infertility or sterility. Oncofertility, an emerging field at the intersection of cancer and oncology, centers on providing cancer patients with the potential to preserve their biological fertility.
We examine the history of how men and women have been treated for infertility and analyze contemporary studies of how women without cancer respond to infertility.
Both female and male cancer patients and survivors value their fertility, although there is conflicting evidence on the degree to which women and men value fertility. Some studies have found that women and men value their fertility equally while others found that women value their fertility more than men. Gendered norms around fertility and parenthood seem to be changing, which may minimize these discrepancies.
DISCUSSIONS/CONCLUSIONS: Although oncofertility is a nascent field, infertility is a historically relevant medical condition that is characterized by gendered narratives and norms. An analysis of the historical evolution of the understanding and treatment of infertility leads insight into modern conceptualizations of infertility both generally and in the case of cancer. Understanding these historical and current gendered influences helps to define the current context in which cancer patients are confronting potential infertility.
The insight gained from this analysis can be used to inform clinical practice, offering guidance to healthcare providers approaching cancer patients about potential infertility, regardless of gender.
近年来,癌症检测、治疗和技术的进步提高了生存率。然而,这些救命的治疗方法也可能导致不孕或不育。肿瘤生育学是癌症学和肿瘤学交叉领域的一个新兴领域,其中心是为癌症患者提供保留其生物生育能力的潜力。
我们考察了男性和女性不孕不育治疗的历史,并分析了当代无癌症女性对不孕不育反应的研究。
男性和女性癌症患者和幸存者都重视他们的生育能力,尽管关于女性和男性对生育能力的重视程度存在相互矛盾的证据。一些研究发现,女性和男性对生育能力的重视程度相同,而其他研究则发现女性比男性更重视生育能力。围绕生育和育儿的性别规范似乎正在发生变化,这可能会缩小这些差异。
讨论/结论:尽管肿瘤生育学是一个新兴领域,但不孕不育是一个具有历史意义的医学病症,其特点是存在性别化的叙述和规范。对不孕不育理解和治疗的历史演变的分析,可以深入了解一般情况下和癌症情况下的不孕不育的现代概念。了解这些历史和当前的性别影响有助于确定癌症患者面临潜在不孕不育的当前背景。
从这种分析中获得的见解可以用于为临床实践提供信息,为医疗保健提供者提供指导,无论性别如何,向癌症患者介绍潜在的不孕不育问题。