Institute of Dentistry, University of Oulu, Oulu, Finland.
J Clin Periodontol. 2011 Mar;38(3):236-42. doi: 10.1111/j.1600-051X.2010.01677.x. Epub 2010 Dec 27.
To investigate the role of periodontal infection in obesity in an adult population.
This study was based on a subpopulation of the Health 2000 Survey that included dentate, non-diabetic subjects, aged 30-49 years (n=2784). Obesity was measured using the body mass index (BMI), body fat percentage (BF%) and waist circumference (WC). The extent of periodontal infection was measured using the number of teeth with deepened (4 mm deep or deeper) periodontal pockets and was categorized into four categories (0, 1-3, 4-6, 7 or more).
The number of teeth with deepened periodontal pockets was found to be associated with BMI in an exposure-response manner among the total study population. The association was found among men and women, and also among never-smokers. The number of teeth with deepened periodontal pockets was also associated with BF% and WC among never-smokers.
Periodontal infection measured by means of the number of teeth with deepened periodontal pockets appears to be associated with obesity. However, no inferences about causality can be made and further studies are needed to clarify the possible role of periodontal infection in obesity.
探讨成年人牙周感染与肥胖的关系。
本研究基于 2000 年健康调查的一个亚组,包括有牙、非糖尿病、年龄在 30-49 岁的人群(n=2784)。肥胖通过体重指数(BMI)、体脂肪百分比(BF%)和腰围(WC)来衡量。牙周感染程度通过牙周袋深度(4 毫米或更深)的牙齿数量来衡量,并分为四个类别(0、1-3、4-6、7 个或更多)。
在总研究人群中,牙周袋深度增加的牙齿数量与 BMI 呈暴露反应关系。这种关联在男性和女性中均存在,在从不吸烟的人群中也存在。在从不吸烟的人群中,牙周袋深度增加的牙齿数量也与 BF%和 WC 相关。
通过牙周袋深度增加的牙齿数量来衡量的牙周感染似乎与肥胖有关。然而,不能得出因果关系的推论,需要进一步的研究来阐明牙周感染在肥胖中的可能作用。