双硫仑神经病

Disulfiram neuropathy.

作者信息

Moddel G, Bilbao J M, Payne D, Ashby P

出版信息

Arch Neurol. 1978 Oct;35(10):658-60. doi: 10.1001/archneur.1978.00500340034006.

DOI:10.1001/archneur.1978.00500340034006

PMID:211996

Abstract

A 35-year-old man developed a distal sensorimotor polyneuropathy after taking disulfiram, 500 mg daily for five months. His symptoms improved after the drug therapy was discontinued. Clinical, electrophysiological, and pathological observations during the acute stage and during recovery suggest that disulfiram produces a distal axonopathy.

摘要

一名35岁男性在每日服用500毫克双硫仑五个月后出现了远端感觉运动性多发性神经病。停药后他的症状有所改善。急性期和恢复过程中的临床、电生理及病理观察表明，双硫仑可导致远端轴索性神经病。