Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Semin Neurol. 2010 Nov;30(5):469-76. doi: 10.1055/s-0030-1268868. Epub 2011 Jan 4.
The management of acute ischemic stroke has advanced greatly over the past 2 decades. New interventions, including intravenous and endovascular treatment strategies, have evolved to recanalize arteries and salvage the ischemic brain. The evolution of interventional approaches to the treatment of acute stroke has been prompted by the limitations of intravenous therapy and intended to extend the treatment window, improve recanalization rates, and subsequently long-term clinical outcomes. The major techniques that have defined the current field of interventional acute stroke management and the relevant past and current data, and ongoing clinical trials on interventional stroke therapy will be reviewed. New issues, such as futile recanalization, and time to microcatheter, will also be discussed.
在过去的 20 年中,急性缺血性脑卒中的治疗取得了重大进展。新的干预措施,包括静脉内和血管内治疗策略,已经发展到可以使动脉再通并挽救缺血性大脑。急性脑卒中治疗的介入方法的发展是由于静脉内治疗的局限性,并旨在延长治疗时间窗,提高再通率,从而改善长期临床结局。本综述将回顾目前介入性急性脑卒中管理领域的主要技术,以及相关的过去和当前数据,以及正在进行的介入性脑卒中治疗的临床试验。还将讨论新出现的问题,如无效再通和微导管时间。