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资源竞争与宿主内疾病动态。

Resource competition and within-host disease dynamics.

机构信息

Val Smith is at the Dept of Systematics and Ecology, and Environmental Studies Program, University of Kansas, Lawrence, KS 66045, USA; Robert Holt is at the Dept of Systematics and Ecology, and the Natural History Museum, University of Kansas, Lawrence, KS 66045, USA.

出版信息

Trends Ecol Evol. 1996 Sep;11(9):386-9. doi: 10.1016/0169-5347(96)20067-9.

Abstract

The host organism is a complex mosaic of cell populations that requires adequate supplies of nutrients for maintenance, growth and proliferation. Because many nutrient requirements may be shared by host cells, pathogens and indigenous microflora, all these cells may potentially compete for growth-limiting resources. Ecological theory can explain some of the dynamics commonly seen in host-pathogen interactions; and mechanistic resource-consumer theory provides an instructive framework for viewing the disease process.

摘要

宿主生物体是细胞群体的复杂镶嵌体,需要充足的营养供应才能维持、生长和增殖。由于宿主细胞、病原体和土著微生物群落的许多营养需求可能是共享的,因此所有这些细胞都可能潜在地争夺生长受限的资源。生态理论可以解释在宿主-病原体相互作用中常见的一些动态;而机制资源消费者理论为观察疾病过程提供了一个有益的框架。

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