Department of Dermatology, Konkuk University School of Medicine, Gwangjin-gu, Seoul 143-729, Korea.
Br J Dermatol. 2011 Jun;164(6):1356-61. doi: 10.1111/j.1365-2133.2011.10225.x. Epub 2011 May 9.
Persistent pigment darkening (PPD) is a widely used in vivo method for measurement of ultraviolet (UV) A protection factor (UVAPF). However, with increased emphasis on UVA protection and sunscreen products with higher UVAPF gaining popularity, the immediate pigment darkening (IPD) method is drawing attention again. Furthermore, only about a quarter of the recommended quantity of sunscreen is used during daily activities. However, there is as yet no clearly defined relationship between the UVAPF and the amount of sunscreen applied.
To analyse the differences between the IPD and PPD methods, and to establish a relationship between the quantity of sunscreen application and the UVAPF.
Different doses of sunscreen were applied on the back of 15 healthy volunteers, and the UVAPF was measured using both the IPD and the PPD methods.
Both methods proved to be effective for measuring the UVAPF. However, all the UVAPF values determined by the PPD method were lower than those determined by the IPD method. Additionally, an exponential relationship between the amount of sunscreen applied and the UVAPF was observed.
The IPD method can also be used as an appropriate endpoint in the determination of UVA protection. It is time saving, and thus considerably lowers the risk of UV exposure, particularly when testing sunscreen products with higher UVAPF. We further state that in order to achieve the desired protective effect of the sunscreen, the quantity of application is also very important.
持久色素沉着(PPD)是一种广泛用于测量紫外线(UV)A 防护因子(UVAPF)的体内方法。然而,随着对 UVA 保护的重视以及具有更高 UVAPF 的防晒产品越来越受欢迎,即时色素沉着(IPD)方法再次引起关注。此外,在日常活动中,人们仅使用了推荐防晒霜用量的约四分之一。然而,目前仍然没有明确界定防晒用量与 UVAPF 之间的关系。
分析 IPD 和 PPD 方法之间的差异,并建立防晒用量与 UVAPF 之间的关系。
在 15 名健康志愿者的背部涂抹不同剂量的防晒霜,分别使用 IPD 和 PPD 方法测量 UVAPF。
两种方法均能有效测量 UVAPF。然而,PPD 方法确定的所有 UVAPF 值均低于 IPD 方法确定的值。此外,观察到防晒用量与 UVAPF 之间存在指数关系。
IPD 方法也可作为确定 UVA 保护的适当终点。它省时省力,因此大大降低了紫外线暴露的风险,尤其是在测试具有更高 UVAPF 的防晒产品时。我们进一步指出,为了实现防晒霜的预期保护效果,防晒用量也非常重要。