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2010年肝细胞癌的放射治疗

[Radiological treatment of hepatocellular carcinoma in 2010].

作者信息

Rode A

机构信息

Service d'imagerie médicale, hôpital de la Croix-Rousse, 93 grande rue de la Croix-Rousse, Lyon cedex 04, France.

出版信息

Cancer Radiother. 2011 Feb;15(1):21-7. doi: 10.1016/j.canrad.2010.11.002. Epub 2011 Jan 22.

Abstract

Several radiological techniques have been used for treating hepatocellular carcinoma. These include transcatheter arterial chemoembolization (TACE) and percutaneous therapy, such as radiofrequency (RF). The treatment efficacy of radiofrequency for hepatocellular carcinoma has been confirmed by several randomized and non randomized studies, with a benefit in terms of morbidity comparatively to surgery when cirrhosis is present. Radiofrequency ablation treatment is based on tumour size, shape and location, with a defined strategy and a proper patient selection. We will also review indications and technical aspects of transcatheter arterial chemoembolization (TACE). It is an accepted worldwide and effective treatment for patients with unresectable large or multinodular hepatocellular carcinoma. It improves significantly survival for adequate selected patients with preservation of liver function.

摘要

几种放射学技术已被用于治疗肝细胞癌。这些技术包括经导管动脉化疗栓塞术(TACE)和经皮治疗,如射频(RF)。多项随机和非随机研究证实了射频治疗肝细胞癌的疗效,当存在肝硬化时,与手术相比,其在发病率方面具有优势。射频消融治疗基于肿瘤的大小、形状和位置,采用明确的策略并进行适当的患者选择。我们还将回顾经导管动脉化疗栓塞术(TACE)的适应证和技术方面。它是一种被全球认可的、对不可切除的大或多结节肝细胞癌患者有效的治疗方法。对于适当选择的肝功能得以保留的患者,它能显著提高生存率。

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