Department of General Surgery, Medical School, Dicle University, Yenişehir, 21280, Diyarbakır, Turkey.
Biol Trace Elem Res. 2011 Dec;143(3):1282-8. doi: 10.1007/s12011-011-8965-5. Epub 2011 Jan 27.
Laparoscopic adjustable gastric banding (LAGB) causes significant weight loss in morbidly obese adults. However, its consequences on nutritional status still remain unclear. There are a few studies determining the nutritional status after LAGB and none have focused on the serum levels of zinc (Zn), copper (Cu), and ceruloplasmin (CP). We aimed to investigate the effects of LAGB surgery on plasma Zn, Cu, and CP levels. Thirty patients with LAGB with morbid obesity were included. Blood samples were collected preooperatively and in the postoperative third month to determine plasma Zn, Cu, and CP levels. The mean preoperative and postoperative body mass indexes (BMI) were 44.9 ± 7.4 kg/m(2) and 44.1 ± 6.5 kg/m(2), respectively. The mean weight loss was 12.9 ± 3.3 kg at the postoperative third month. The postoperative Zn (500 ± 130 ng/ml), Cu (280 ± 80 ng/ml), and CP (23.9 ± 8.8 mg/dl) values were statistically significantly lower than the preooperative Zn (740 ± 230 ng/ml), Cu (370 ± 80 ng/ml) and CP (33.3 ± 15.7 mg/dl) levels (p < 0.05). Decreases in the plasma levels of Zn, Cu, and CP were seen postoperatively following LAGB surgery. The nutritional status of LAGB-applied patients should be monitored and mineral supplementation may be considered.
腹腔镜可调节胃束带术(LAGB)可使病态肥胖的成年人显著减重。然而,其对营养状况的影响仍不清楚。有一些研究确定了 LAGB 后的营养状况,但没有一项研究集中在锌(Zn)、铜(Cu)和铜蓝蛋白(CP)的血清水平上。我们旨在研究 LAGB 手术对血浆 Zn、Cu 和 CP 水平的影响。
我们纳入了 30 名患有病态肥胖的 LAGB 患者。术前和术后第三个月采集血样,以确定血浆 Zn、Cu 和 CP 水平。术前和术后第三个月的平均体重指数(BMI)分别为 44.9 ± 7.4 kg/m2和 44.1 ± 6.5 kg/m2。术后第三个月的平均体重减轻量为 12.9 ± 3.3 kg。术后 Zn(500 ± 130 ng/ml)、Cu(280 ± 80 ng/ml)和 CP(23.9 ± 8.8 mg/dl)值明显低于术前 Zn(740 ± 230 ng/ml)、Cu(370 ± 80 ng/ml)和 CP(33.3 ± 15.7 mg/dl)水平(p < 0.05)。LAGB 手术后,血浆 Zn、Cu 和 CP 水平均降低。LAGB 应用患者的营养状况应进行监测,可能需要补充矿物质。