Musto R J
Can Fam Physician. 1986 Jan;32:125-9.
Evidence relating adverse pregnancy outcome to maternal alcohol use seldom focuses on nonabusive levels of drinking, yet this is what the majority of patients seek information about. Outcomes of the hypothesized mechanisms of action appear related to pattern of exposure and timing during pregnancy. Methodological problems encountered in human studies include determination of exposure, method of analysis, and outcome measurement. Physicians should be aware of drinking habits of women in the childbearing years, and the reported adverse effects of moderate drinking. Guidelines for alcohol use in pregnancy are suggested.
将不良妊娠结局与孕妇饮酒相关的证据很少关注非滥用水平的饮酒情况,然而这正是大多数患者寻求信息的内容。推测的作用机制的结果似乎与孕期的接触模式和时间有关。人体研究中遇到的方法学问题包括接触的确定、分析方法和结局测量。医生应该了解育龄妇女的饮酒习惯,以及适度饮酒的报告不良影响。建议制定孕期饮酒指南。