在评估适合进行切除性癫痫手术的患者时使用深部电极的8年经验。

An 8-year experience with depth electrodes in the evaluation of ablative seizure surgery candidates.

作者信息

Smith J R, Flanigin H F, King D W, Gallagher B B, Murro A M, Holmes G L, Campbell L R, Lee G, Wheless J

机构信息

Division of Neurosurgery, Medical College of Georgia, Augusta.

出版信息

Stereotact Funct Neurosurg. 1990;54-55:60-6. doi: 10.1159/000100191.

DOI:10.1159/000100191

PMID:2127862

Abstract

Stereotactically implanted depth electrodes are one means of localization of seizure foci. Unilateral seizure focus localization was obtained in 72.7% mesial temporal (MT) implants and 50% of focus/extramesial temporal (MT-XMT) implants. Recent increase in localization to over 80% in MT implants was possible because a larger percentage of patients had MT-XMT implants. Increased localization to 60% in MT-XMT implants was related to using more XMT electrodes per patient and to orienting electrodes to monitor larger limbic XMT and neocortical areas. Since MT foci were localized in 25% of MT-XMT cases, MT electrodes should be included with all MT-XMT implants. Depth electrography can also be used to rule out certain patients as surgical candidates. Therefore, a surgical decision can be reached in a very high percentage of patients undergoing depth implantation. Surgical results are comparable to those in our overall series.

摘要

立体定向植入深度电极是癫痫病灶定位的一种方法。在72.7%的内侧颞叶（MT）植入病例和50%的病灶/颞叶外区域（MT-XMT）植入病例中实现了单侧癫痫病灶定位。MT植入病例中近期定位率增加到80%以上是因为有更大比例的患者进行了MT-XMT植入。MT-XMT植入病例中定位率增加到60%与每位患者使用更多的XMT电极以及将电极定向以监测更大的边缘系统XMT和新皮质区域有关。由于在25%的MT-XMT病例中发现了MT病灶，所有MT-XMT植入都应包含MT电极。深度脑电图检查也可用于排除某些患者作为手术候选者。因此，在接受深度植入的患者中，很高比例的患者能够做出手术决策。手术结果与我们整个系列的结果相当。