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眼-面-呼吸评分是评估重症肌无力患者球部功能的一种工具。

The Oculobulbar Facial Respiratory score is a tool to assess bulbar function in myasthenia gravis patients.

机构信息

Institute of Neurological Sciences, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, UK.

出版信息

Muscle Nerve. 2011 Mar;43(3):329-34. doi: 10.1002/mus.21880. Epub 2011 Feb 8.

Abstract

The Oculobulbar Facial Respiratory (OBFR) score is a tool that objectively measures bulbar function in myasthenia gravis (MG). In this study, we analyzed the relation between the OBFR and the MG Activities of Daily Living (MG-ADL) score, and also with the more recently described MG Composite and 15-item MG Quality-of-Life (MG-QOL15) scales. We recruited 42 patients from two centers and assessed them on two occasions, approximately 6 months apart, using the OBFR, MG Composite, MG-ADL, and MG-QOL15 scales. The 'modified' OBFR score was derived from the original OBFR score. The OBFR score correlated significantly with the MG Composite, MG-ADL, and MG-QOL15 scores for both assessments, and with the sum of the bulbar items for all three scores. It also correlated strongly with the individual bulbar-related items of all three scores. The 'modified' OBFR score also correlated significantly with all the aforementioned scores. This study confirmed construct validity of the OBFR and 'modified' OBFR scores.

摘要

眼-面-呼吸(OBFR)评分是一种客观测量重症肌无力(MG)球部功能的工具。本研究分析了 OBFR 与 MG 日常生活活动(MG-ADL)评分之间的关系,以及与最近描述的 MG 综合评分和 15 项 MG 生活质量(MG-QOL15)评分之间的关系。我们从两个中心招募了 42 名患者,并在大约 6 个月的时间里两次使用 OBFR、MG 综合评分、MG-ADL 和 MG-QOL15 评分对他们进行评估。“改良”OBFR 评分是从原始 OBFR 评分中得出的。在两次评估中,OBFR 评分与 MG 综合评分、MG-ADL 评分和 MG-QOL15 评分均显著相关,与所有三个评分的球部项目总和也显著相关。它还与所有三个评分的各个与球部相关的项目密切相关。“改良”OBFR 评分也与上述所有评分显著相关。本研究证实了 OBFR 和“改良”OBFR 评分的结构效度。

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