A comparison of the effectiveness between amniotic membrane homogenate and transplanted amniotic membrane in healing corneal damage in a rabbit model.

PURPOSE

To determine whether amniotic membrane homogenate is as effective in healing corneal damage as amniotic membrane transplantation in a rabbit model.

METHOD

The rabbits were divided into three groups. The cornea of one eye in each rabbit was incised resulting in a defect of approximately 8 mm in diameter. Amniotic membrane transplantation was performed in the first group, and amnion homogenate was administered four times a day in the second group. The third group was the control group.

RESULTS

There were no differences in the diameter of the defects and the rate of corneal growth between the amnion transplant group and the amnion homogenate group.

CONCLUSION

Amnion homogenate is as effective as transplanted amniotic membrane in promoting corneal healing in a rabbit model.