Division of Gastroenterology and Hepatology, Mayo Clinic Florida, Jacksonville, FL, USA.
Dig Liver Dis. 2011 Jun;43(6):470-4. doi: 10.1016/j.dld.2011.01.003. Epub 2011 Feb 11.
Doppler transabdominal ultrasound is a validated screening test for chronic mesenteric ischaemia, but gas and obesity are limitations. Endoscopic ultrasound has been proposed as a comprehensive test to evaluate chronic upper abdominal pain and is capable of Doppler measurement. We aim to evaluate the accuracy of Doppler endoscopic ultrasound (D-EUS) as a single screening test to rule out chronic mesenteric ischaemia in patients with abdominal pain and compare it with Doppler transabdominal ultrasound (D-TUS).
We enrolled all patients ≥50 years with chronic upper abdominal pain and vascular risk referred for endoscopic ultrasound. All were scheduled for D-EUS and D-TUS plus a confirmatory test if one of the previous resulted positive. We estimated the accuracy of both techniques comparing them using McNemar test.
68 patients completed the study. Fifty-three (78%) underwent D-EUS, D-TUS, and a confirmatory test. Fifteen (38%) underwent follow-up after negative results. Three (4%) in the D-EUS group and 14 in the D-TUS (21%) were excluded due to artefacts. D-EUS presented a sensitivity of 63%, specificity of 84%, whilst D-TUS presented a sensitivity of 80% and a specificity of 78%. Specificity of D-EUS was not significantly different to D-TUS.
These results support the role of Doppler endoscopic ultrasound to exclude chronic mesenteric ischaemia as cause of chronic abdominal pain.
经腹部多普勒超声是一种经过验证的慢性肠系膜缺血筛查试验,但气体和肥胖是其限制因素。内镜超声已被提议作为一种全面的测试方法,用于评估慢性上腹痛,并能够进行多普勒测量。我们旨在评估多普勒内镜超声(D-EUS)作为单一筛查试验排除腹痛患者慢性肠系膜缺血的准确性,并将其与经腹部多普勒超声(D-TUS)进行比较。
我们招募了所有≥50 岁的、有慢性上腹痛和血管风险的患者,并将其转介进行内镜超声检查。所有患者均计划进行 D-EUS 和 D-TUS 检查,如果其中一项检查结果阳性,则进行确认性检查。我们使用 McNemar 检验比较两种技术的准确性。
68 例患者完成了研究。53 例(78%)患者进行了 D-EUS、D-TUS 和确认性检查。15 例(38%)患者在阴性结果后进行了随访。D-EUS 组中有 3 例(4%)和 D-TUS 组中有 14 例(21%)因伪影而被排除。D-EUS 的敏感性为 63%,特异性为 84%,而 D-TUS 的敏感性为 80%,特异性为 78%。D-EUS 的特异性与 D-TUS 无显著差异。
这些结果支持使用多普勒内镜超声排除慢性肠系膜缺血作为慢性腹痛的原因。