干预激素依赖性癌症治疗的副作用：力量训练的作用。
Intervening on the side effects of hormone-dependent cancer treatment: the role of strength training.
作者信息
Hanson Erik D, Hurley Ben F
机构信息
Department of Kinesiology, School of Public Health, University of Maryland, College Park, MD 20742, USA.
出版信息
J Aging Res. 2011 Jan 13;2011:903291. doi: 10.4061/2011/903291.
While prostate and breast cancers are both highly prevalent and treatable using hormone suppression therapy, a constellation of side effects ensue, which mimic typical aging effects but at an accelerated pace. Because strength training is considered to be an intervention of choice for addressing the musculoskeletal and metabolic consequences of normal aging in older adults, it may be an effective intervention to attenuate or reverse the side effects of hormone-dependent cancer treatment. This paper provides an overview of the independent effects of strength training on common musculoskeletal and metabolic side effects of hormone-dependent therapy used for prostate and breast cancers. Strength training appears to be an effective complementary therapy for some of the adverse effects of prostate and breast treatment. Future research needs to address potential mechanisms to explain recent findings and to explore the role of strength training in addressing specific risk factors resulting from cancer treatment.
虽然前列腺癌和乳腺癌都非常常见，且可通过激素抑制疗法进行治疗，但随之会出现一系列副作用，这些副作用模仿典型的衰老效应，但速度更快。由于力量训练被认为是解决老年人正常衰老的肌肉骨骼和代谢后果的首选干预措施，因此它可能是减轻或逆转激素依赖性癌症治疗副作用的有效干预措施。本文概述了力量训练对用于前列腺癌和乳腺癌的激素依赖性疗法常见的肌肉骨骼和代谢副作用的独立影响。力量训练似乎是前列腺癌和乳腺癌治疗某些不良反应的有效补充疗法。未来的研究需要探讨潜在机制以解释最近的发现，并探索力量训练在解决癌症治疗导致的特定风险因素方面的作用。
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