Ilyas Sadaf, Youssef Dima, Chaudhary Humera, Al-Abbadi Mousa A
Department of Pathology and Laboratory Medicine, James H Quillen VA Medical Center, Lamont and Veterans Way, PO Box 4000, Mountain Home, TN 37684, USA.
Head Neck Pathol. 2011 Sep;5(3):296-301. doi: 10.1007/s12105-011-0248-0. Epub 2011 Feb 16.
In this case report, we describe an unusual case of mycobacterial associated inflammatory pseudotumor that occurred in a patient with a previous history of cocaine abuse. We discuss inflammatory pseudotumor (IPT) in general and emphasize the rare entity where an associated mycobacterial infection is seen. The histogenesis is not yet completely understood. The lesion can pose challenges for practicing pathologists and a misdiagnosis of malignancy can occur at multiple facets. A discussion about the differential diagnosis and clues to make the distinction is presented. In addition to spindle cell proliferation, the presence of a background of mixed inflammatory cell infiltrate and foamy macrophages are clues to make the diagnosis. In the case of mycobacteria associated IPT, Acid Fast Bacilli (AFB) stains will easily highlight the organisms confirming the diagnosis.
在本病例报告中,我们描述了一例发生在有可卡因滥用史患者身上的不寻常的分枝杆菌相关炎性假瘤病例。我们总体讨论炎性假瘤(IPT),并强调出现相关分枝杆菌感染这种罕见情况。其组织发生尚未完全明确。该病变会给病理科医生带来挑战,在多个方面可能出现恶性肿瘤的误诊情况。本文还介绍了关于鉴别诊断及鉴别的线索。除梭形细胞增生外,混合性炎性细胞浸润背景和泡沫状巨噬细胞的存在是做出诊断的线索。在分枝杆菌相关IPT病例中,抗酸杆菌(AFB)染色能轻易突显病原体从而确诊。