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[非结核分枝杆菌性淋巴结炎伴新出现病原体及新的管理方法]

[Nontuberculous mycobacterial lymphadenitis with an emerging pathogen and a novel management approach].

作者信息

Waisbourd-Zinman Orit, Eidlitz-Markus Tal, Zeharia Avraham, Haimi-Cohen Yishai

机构信息

Day Hospitalization Unit, Department of Pediatrics A, Schneider ChiIdren's Medical Center of Israel, Petah Tikva.

出版信息

Harefuah. 2010 Aug;149(8):490-3, 552.

Abstract

Nontuberculous mycobacterial infections in immunocompetent children usually presents as chronic lymphadenitis involving the neck and face. Mycobacterium avium complex is the most common pathogen, although recent series found Mycobacterium haemophilum, to be a major cause of chronic lymphadenitis in otherwise healthy children. The authors describe a 9-month-old baby who presented with a 4-month history of preauricular lymphadenitis. Mycobacterial culture yielded Mycobacterium haemophilum. A no-intervention approach was chosen. At the 6-month follow-up, the swelling had ameliorated and the skin showed a small scar with near-normal overlying skin color. A literature review of the clinical manifestations and diagnosis of Mycobacterium haemophilum lymphadenitis and of the different management options for nontuberculous mycobacterial lymphadenitis in otherwise healthy children is presented.

摘要

免疫功能正常儿童的非结核分枝杆菌感染通常表现为累及颈部和面部的慢性淋巴结炎。鸟分枝杆菌复合体是最常见的病原体,不过最近的系列研究发现嗜血性分枝杆菌是原本健康儿童慢性淋巴结炎的主要病因。作者描述了一名9个月大的婴儿,其患有4个月的耳前淋巴结炎病史。分枝杆菌培养结果为嗜血性分枝杆菌。选择了不干预的方法。在6个月的随访中,肿胀有所改善,皮肤出现一个小疤痕,其上覆皮肤颜色接近正常。本文对嗜血性分枝杆菌淋巴结炎的临床表现、诊断以及原本健康儿童非结核分枝杆菌淋巴结炎的不同治疗选择进行了文献综述。

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