Department of Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan.
Eur J Cardiothorac Surg. 2011 Oct;40(4):1007-10. doi: 10.1016/j.ejcts.2011.01.022. Epub 2011 Feb 26.
In the long-term period after Fontan operation, atrial arrhythmia was one of the important factors to decide the postoperative quality of life. We reviewed the impact of Fontan conversion with arrhythmia surgery and pacemaker therapy.
Thirty-eight patients underwent Fontan conversion using extracardiac conduit from 1992, and 22 patients with atrial arrhythmia underwent maze procedure simultaneously using cryoablation or radiofrequency ablation and epicardial DDD pacemaker implantation and 16 patients had regular 'sinus' rhythm before Fontan conversion. Mean follow-up period was 52 months. Pre- and postoperative clinical course were analyzed. Average weight, age at Fontan conversion, and years after first Fontan operation were 49.0 kg, 25.8 years old, 14.7 years, respectively. Nineteen percent of patients were in New York Heart Association class I (NYHA I), and 74% of patients were in NYHA II, and 7% were in NYHA III, respectively.
Except three early deaths, actual survival rate at 1 year and 5 years were 80% and 64%, respectively. In survivors, 80% of the patients obtained regular heart rhythm including artificial pacemaker rhythm, although only 43% of the patients had regular 'sinus' rhythm before the Fontan conversion. Postoperative average cardiothoracic ratio and oxygen saturation (SpO(2)) were 50% and 94%, and 74% of patients were in NYHA I and 26% were in NYHA II, respectively, after Fontan conversion.
Mid-term results of Fontan conversion with arrhythmia surgery and pacemaker therapy were acceptable. Restoration of regular rhythm might improve the postoperative NYHA status and the activity of the daily life.
在法乐四联症根治术后的长期随访中,房性心律失常是影响患者术后生活质量的重要因素之一。我们回顾了心律失常手术及起搏器治疗对法乐四联症根治术后患者的影响。
1992 年以来,我们对 38 例患者采用体外循环下心外管道行 Fontan 转换术,其中 22 例房性心律失常患者同期行迷宫手术,采用冷冻或射频消融,并在心外膜植入双腔起搏器;16 例患者在 Fontan 转换术前有窦性心律。平均随访时间为 52 个月。分析患者术前和术后的临床过程。平均体重、Fontan 转换时年龄和首次 Fontan 手术后时间分别为 49.0kg、25.8 岁和 14.7 年。19%的患者纽约心功能分级(NYHA)为Ⅰ级,74%的患者为Ⅱ级,7%的患者为Ⅲ级。
除 3 例早期死亡外,1 年和 5 年的实际生存率分别为 80%和 64%。在幸存者中,尽管只有 43%的患者在 Fontan 转换前有窦性心律,但 80%的患者获得了规则的心律,包括人工起搏器心律。术后心胸比率和血氧饱和度(SpO2)平均值分别为 50%和 94%,74%的患者 NYHA 分级为Ⅰ级,26%的患者 NYHA 分级为Ⅱ级。
心律失常手术及起搏器治疗的中期结果是可以接受的。恢复规则的节律可能改善术后 NYHA 状态和日常生活活动能力。