Janssen O E
Endokrinologikum Hamburg.
Dtsch Med Wochenschr. 2011 Mar;136(11):519-22. doi: 10.1055/s-0031-1274535. Epub 2011 Mar 8.
A 41-year-old woman had been treated with an antibiotic for a sore throat and a tender neck. Later, moderate hyperthyroidism developed and was treated with antithyroid drugs. She presented herself for further work-up when neck pain and malaise persisted. On palpation, the thyroid was tender and firm, but not enlarged. Signs and symptoms indicated moderate hyperthyroidism.
Laboratory findings included suppressed TSH, elevated thyroid hormones, and both elevated erythrocyte sedimentation rate and CRP. On ultrasound, the thyroid was found to be of normal size but severely hypoechoic. A thyroid scan showed low uptake of technetium.
The findings supported the diagnosis of subacute thyroiditis. Prednisolone treatment provided relief of pain within 2 days. The patient later developed hypothyroidism suggestive of Hashimoto's thyroiditis and required thyroxin supplementation.
一名41岁女性因喉咙疼痛和颈部压痛接受了抗生素治疗。后来,出现了中度甲状腺功能亢进,并接受了抗甲状腺药物治疗。当颈部疼痛和不适持续存在时,她前来进行进一步检查。触诊时,甲状腺有压痛且质地坚硬,但未肿大。体征和症状表明为中度甲状腺功能亢进。
实验室检查结果包括促甲状腺激素(TSH)降低、甲状腺激素升高,红细胞沉降率和C反应蛋白(CRP)均升高。超声检查显示甲状腺大小正常,但回声严重减低。甲状腺扫描显示锝摄取率低。
这些检查结果支持亚急性甲状腺炎的诊断。泼尼松龙治疗在2天内缓解了疼痛。该患者后来出现了提示桥本甲状腺炎的甲状腺功能减退,需要补充甲状腺素。