Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 712 Eonjuro, Seoul, Korea.
J Korean Med Sci. 2011 Mar;26(3):457-60. doi: 10.3346/jkms.2011.26.3.457. Epub 2011 Feb 25.
Tuberculosis remains one of the most prevalent and fatal infectious diseases in spite of considerable improvements in medical science. The diagnosis and treatment of extrapulmonary tuberculosis involving the abdomen is still complicated owing to vague or non-specific clinical features. Although rare, isolated splenic involvement is one of the important manifestations of extrapulmonary tuberculosis, and imaging suspicion of the disease is essential. We report a case of surgically confirmed mass-forming splenic tuberculosis showing a layered pattern consisting of caseous necrosis with profound restriction of water molecules surrounded by an irregular rind of granulation tissue with less diffusion restriction on diffusion-weighted magnetic resonance imaging (DWI). In the differential diagnosis of neoplastic or non-neoplastic mass-forming lesions involving the spleen, this unique DWI feature could be helpful in characterizing splenic tuberculosis. The patient has been in clinically disease free status for nearly 20 months after splenectomy.
尽管医学科学取得了相当大的进步,但结核病仍然是最普遍和最致命的传染病之一。由于腹部肺外结核病的临床表现模糊或非特异性,其诊断和治疗仍然很复杂。虽然罕见,但孤立性脾脏受累是肺外结核病的重要表现之一,对该病的影像学怀疑是必要的。我们报告了一例经手术证实的肿块形成性脾结核,其表现为分层模式,包括干酪样坏死,水分子明显受限,周围为不规则的肉芽组织环,弥散受限较轻。在鉴别诊断涉及脾脏的肿瘤或非肿瘤性肿块形成病变时,这种独特的 DWI 特征有助于脾结核的特征化。患者在脾切除术后近 20 个月一直处于临床无病状态。