Genes in inflammatory bowel disease: lessons from complex diseases.
作者信息
Henderson Paul, Satsangi Jack
出版信息
Clin Med (Lond). 2011 Feb;11(1):8-10. doi: 10.7861/clinmedicine.11-1-8.
Abstract
摘要
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Am J Gastroenterol. 2010 Aug;105(8):1811-9. doi: 10.1038/ajg.2010.95. Epub 2010 Mar 2.
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Variants at the 3p21 locus influence susceptibility and phenotype both in adults and early-onset patients with inflammatory bowel disease.3p21 位点的变异既影响成人炎症性肠病患者的易感性，也影响其表型，也影响早发性炎症性肠病患者的易感性和表型。
Inflamm Bowel Dis. 2010 Jul;16(7):1108-17. doi: 10.1002/ibd.21176.
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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation.NOD2 刺激诱导树突状细胞自噬，影响细菌处理和抗原呈递。
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Natural history and complications of IBD.炎症性肠病的自然病史及并发症
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Nat Immunol. 2010 Jan;11(1):55-62. doi: 10.1038/ni.1823. Epub 2009 Nov 8.
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