N-杂环卡宾催化 3,5-二氯-2(1H)-吡嗪酮的芳基化反应。

N-heterocyclic carbene catalyzed aroylation of 3,5-dichloro-2(1H)-pyrazinones.

机构信息

Laboratory for Organic & Microwave-Assisted Chemistry, Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, B-3001 Leuven, Belgium.

出版信息

J Org Chem. 2011 Apr 15;76(8):2920-5. doi: 10.1021/jo200155n. Epub 2011 Mar 15.

DOI:10.1021/jo200155n

PMID:21405078

Abstract

The N-heterocyclic carbene catalyzed chemoselective C3-aroylation of 3,5-dichloro-2(1H)-pyrazinones with various aldehydes is reported. We herein describe results of this remarkable mild and efficient procedure.

摘要

报道了 N-杂环卡宾催化的 3,5-二氯-2(1H)-吡嗪酮与各种醛的 C3-芳基化的选择性反应。本文详细描述了这一显著温和高效的方法的结果。