2B 型多发性内分泌肿瘤和 1 型神经纤维瘤病患者双侧下颌下腺嗜酸性细胞瘤：不常见病例。

Bilateral submandibular gland oncocytoma in a patient with multiple endocrine neoplasia 2B syndrome and neurofibromatosis type 1: an unusual case.

机构信息

Department of Oral and Maxillofacial Surgery, The Royal Melbourne Hospital of Melbourne, Melbourne, Australia.

出版信息

Int J Oral Maxillofac Surg. 2011 Jul;40(7):764-7. doi: 10.1016/j.ijom.2011.02.017. Epub 2011 Mar 17.

DOI:10.1016/j.ijom.2011.02.017

PMID:21419601

Abstract

Oncocytomas are unusual neoplasms of the head and neck that occur mainly in the parotid gland. The authors report a case of bilateral submandibular gland oncocytoma in a patient with multiple endocrine neoplasia 2B syndrome and neurofibromatosis type 1. Histopathology of the resection specimens demonstrated lymphovascular invasion but no other aggressive features. This was a highly unusual feature in an otherwise rare benign tumour.

摘要

头颈部的嗜酸细胞瘤是一种不常见的肿瘤，主要发生在腮腺。作者报告了一例多发性内分泌腺瘤 2B 综合征和 1 型神经纤维瘤病患者双侧颌下腺嗜酸细胞瘤。切除标本的组织病理学显示存在淋巴血管侵犯，但无其他侵袭性特征。这在这种罕见的良性肿瘤中是一个非常不寻常的特征。