棕色脂肪组织的新纪元：棕色脂肪细胞功能与分化的新见解。
A new era for brown adipose tissue: New insights into brown adipocyte function and differentiation.
机构信息
Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Complutense University, 28040 Madrid, Spain.
出版信息
Arch Physiol Biochem. 2011 Jul;117(3):195-208. doi: 10.3109/13813455.2011.560951. Epub 2011 Mar 23.
Until quite recently, brown adipose tissue was considered of metabolic significance only in small mammals and human newborns, since it was thought to disappear rapidly after birth in humans. However, nowadays this tissue is known to play a role in the regulation of energy balance not only in rodents, but also in humans. In this review we highlight new features regarding brown adipose tissue origin and function and revise old paradigms about brown adipocyte differentiation.
直到最近，棕色脂肪组织仅在小型哺乳动物和人类新生儿中被认为具有代谢意义，因为人们认为它在人类出生后会迅速消失。然而，如今人们知道，这种组织不仅在啮齿动物中，而且在人类中，都在能量平衡的调节中发挥作用。在这篇综述中，我们强调了棕色脂肪组织起源和功能的新特征，并修正了关于棕色脂肪细胞分化的旧模式。
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