Wu M, Wang Q, Xu X-F, Xiang J-J
Department of Thoracic Surgery, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Thorac Cardiovasc Surg. 2011 Oct;59(7):443-5. doi: 10.1055/s-0030-1250389. Epub 2011 Mar 25.
Three cases of children, aged 7, 12 and 13 years, respectively, with bronchial mucoepidermoid carcinoma are presented. All patients were primarily misdiagnosed as pneumonitis following common symptoms of prolonged fever, cough, expectoration, and indirect signs of bronchial obstruction by chest roentgenogram, before the tumours in the main bronchi were revealed by chest computed tomography and bronchoscopy. After undergoing lobectomy and systematic lymph node dissection, all three patients recovered uneventfully. Histologically, all the cases were low-grade mucoepidermoid carcinoma; one case additionally had mediastinal lymph node metastasis. The patients have remained in good health during a follow-up of between 1.5 and 6 years. Despite its extremely rare occurrence in childhood, the possibility of bronchial mucoepidermoid carcinoma should be kept in mind when encountering a child presenting with symptoms of recurrent pneumonia.
本文报告了3例支气管黏液表皮样癌患儿,年龄分别为7岁、12岁和13岁。所有患者最初均因长期发热、咳嗽、咳痰等常见症状以及胸部X线片显示的支气管阻塞间接征象而被误诊为肺炎,之后经胸部计算机断层扫描和支气管镜检查发现主支气管内有肿瘤。3例患者均接受了肺叶切除术和系统性淋巴结清扫,术后均顺利康复。组织学检查显示,所有病例均为低级别黏液表皮样癌;1例患者还伴有纵隔淋巴结转移。在1.5至6年的随访期内,患者均保持健康。尽管支气管黏液表皮样癌在儿童时期极为罕见,但遇到有反复肺炎症状的儿童时,应考虑到该病的可能性。