Department of Psychiatry, Division of Geriatric Psychiatry, Queen's University, Kingston, Ontario, Canada.
College of Medicine, University of Sydney, Australia.
J Am Med Dir Assoc. 2011 Oct;12(8):556-564. doi: 10.1016/j.jamda.2010.12.001. Epub 2011 Mar 8.
Dementia and cognitive impairment are known to be risk factors for hip fractures and are associated with increased postoperative morbidity and mortality. Little is known of the prevalence of dementia and cognitive impairment among older adults with hip fractures.
We completed searches of the electronic databases for observational studies and report the prevalence of either dementia or cognitive impairment among individuals with hip fractures. We included studies that reported the prevalence of dementia using standard diagnostic criteria or cognitive impairment as measured on cognitive screening tests. We used random-effects meta-analysis to arrive at pooled estimates of the prevalence of dementia and cognitive impairment.
Five studies reported the prevalence of dementia and 34 studies reported the prevalence of cognitive impairment in older adults with hip fractures. The estimated prevalence of dementia among older adults with hip fractures was 19.2% (95% confidence interval [CI]: 11.4% to 30.6%), whereas the prevalence of cognitive impairment was 41.8% (95% CI: 37.0% to 46.8%). In subgroup analyses, individuals admitted from long-term care were more likely to have dementia when compared with individuals admitted from the community, whereas there were no significant differences in the prevalence of cognitive impairment according to gender or study setting.
We conclude that dementia and cognitive impairment are common among older adults with hip fractures. Clinicians providing care for individuals with hip fractures should be aware of the high prevalence of cognitive impairment in this population. Effective strategies to prevent hip fractures and improve postoperative outcomes for older adults with dementia are needed.
痴呆症和认知障碍是髋部骨折的已知风险因素,与术后发病率和死亡率增加有关。对于髋部骨折的老年人中痴呆症和认知障碍的患病率知之甚少。
我们对观察性研究的电子数据库进行了检索,并报告了髋部骨折患者中痴呆症或认知障碍的患病率。我们纳入了使用标准诊断标准报告痴呆症患病率或使用认知筛查测试测量认知障碍的研究。我们使用随机效应荟萃分析得出痴呆症和认知障碍患病率的汇总估计值。
五项研究报告了痴呆症的患病率,34 项研究报告了髋部骨折老年人认知障碍的患病率。髋部骨折老年人痴呆症的估计患病率为 19.2%(95%置信区间:11.4%至 30.6%),而认知障碍的患病率为 41.8%(95%置信区间:37.0%至 46.8%)。在亚组分析中,与从社区入院的患者相比,从长期护理机构入院的患者更有可能患有痴呆症,而根据性别或研究环境,认知障碍的患病率没有显著差异。
我们的结论是,痴呆症和认知障碍在髋部骨折的老年人中很常见。为髋部骨折患者提供护理的临床医生应该意识到该人群中认知障碍的高患病率。需要有效的策略来预防髋部骨折和改善痴呆症老年患者的术后结局。