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饮酒与 19215 例中老年中国人代谢综合征的关系。

Association between alcohol consumption and metabolic syndrome in 19,215 middle-aged and elderly Chinese.

机构信息

Laboratory of Endocrinology and Metabolism, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.

出版信息

Diabetes Res Clin Pract. 2011 Jun;92(3):386-92. doi: 10.1016/j.diabres.2011.02.033. Epub 2011 Apr 1.

Abstract

AIMS

To assess the association of alcohol consumption with metabolic syndrome (Mets) in a Chinese population.

METHODS

A community-based cross-sectional study was performed in 19,215 participants aged 40 years or over in Shanghai of China during June 2008-April 2009. Information about the alcohol consumption including quantity and type of alcoholic beverage was obtained using a standard questionnaire. Physical examination was performed and fasting blood samples were obtained for the measurements of biochemical indicators.

RESULTS

In male wine-only consumers, after adjusted for age, sex, BMI, education levels, exercise and smoking habit, severe alcohol consumption (≥ 50.0 g/d), compared with non-alcohol consumption, conferred 53% increased risk of having MetS. In women, alcohol consumption did not have relation to the prevalence of Mets. In the beer-only, liquor-only and mixed type consumers, no significant associations between MetS or its components and the quantity of alcohol consumption were detected.

CONCLUSIONS

Our findings suggest that excessive wine consumption (alcohol ≥ 50.0 g/d) is associated with higher prevalence of MetS in Chinese men.

摘要

目的

在中国人群中评估饮酒与代谢综合征(Mets)的相关性。

方法

本研究于 2008 年 6 月至 2009 年 4 月在中国上海进行了一项基于社区的横断面研究,共纳入 19215 名年龄在 40 岁及以上的参与者。使用标准问卷获取有关饮酒量和酒精饮料类型的信息。进行体格检查并采集空腹血样以测量生化指标。

结果

在仅饮用葡萄酒的男性中,在校正年龄、性别、BMI、教育水平、运动和吸烟习惯后,与不饮酒相比,重度饮酒(≥50.0g/d)使患 Mets 的风险增加 53%。在女性中,饮酒与 Mets 的患病率无关。在仅饮用啤酒、仅饮用白酒和混合类型的消费者中,未发现 Mets 或其成分与饮酒量之间存在显著关联。

结论

我们的研究结果表明,过量饮酒(酒精≥50.0g/d)与中国男性 Mets 患病率升高相关。

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