CESAM & Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal.
Ecotoxicol Environ Saf. 2011 Jul;74(5):1265-70. doi: 10.1016/j.ecoenv.2011.03.001. Epub 2011 Apr 3.
Xenobiotics may affect fish endocrine system, making endocrine responses relevant in pollution monitoring. Five critical sites in Ria de Aveiro (Portugal), having different contamination profiles, were assessed in comparison to a reference site (Torreira), focusing on Liza aurata stress (plasma cortisol, glucose and lactate) and thyroidal (plasma thyroid stimulating hormone-TSH, thyroxine-T4 and triiodothyronine-T3) responses. L. aurata at Vagos (PAHs contaminated) and Laranjo (mercury contaminated), respectively, displayed, low cortisol and high glucose as well as lactate levels. Considering thyroidal responses, high TSH levels were found at Laranjo; low T4 levels were found at Barra (subject to naval traffic) and low T3 levels were found at Rio Novo do Principe (near a former bleached kraft pulp mill effluent), Laranjo and Vagos. The integrated biomarker index ranked impacted sites as: Laranjo>Vagos>Gafanha>Rio Novo do Principe>Barra>Torreira. Endocrine responses reflected xenobiotics exposure suggesting environmental risk to fish at Ria de Aveiro. However no clear relation was found between stress and thyroidal responses.
环境污染物可能会影响鱼类的内分泌系统，因此内分泌反应在污染监测中具有重要意义。本研究选择葡萄牙阿威罗河口的 5 个具有不同污染特征的关键地点（巴约斯、拉兰霍、加法尼亚、里奥诺沃多普林西佩和巴拉）与一个参考地点（托雷拉）进行了比较，重点研究了欧洲星鳗的应激（血浆皮质醇、葡萄糖和乳酸）和甲状腺（血浆促甲状腺激素-TSH、甲状腺素-T4 和三碘甲状腺原氨酸-T3）反应。巴约斯（多环芳烃污染）和拉兰霍（汞污染）的欧洲星鳗分别表现出皮质醇水平低、葡萄糖和乳酸水平高。就甲状腺反应而言，拉兰霍的 TSH 水平较高；巴拉（受海军交通影响）的 T4 水平较低，里奥诺沃多普林西佩（靠近一家前漂白纸浆厂废水排放口）、拉兰霍和巴约斯的 T3 水平较低。综合生物标志物指数将受影响的地点排名为：拉兰霍>巴约斯>加法尼亚>里奥诺沃多普林西佩>巴拉>托雷拉。内分泌反应反映了环境污染物的暴露，表明阿威罗河口的鱼类面临环境风险。然而，应激和甲状腺反应之间没有明显的关系。
