[严重肾病综合征揭示的系统性淀粉样变性]

[Systemic amyloidosis revealed by an intense nephrotic syndrome].

作者信息

Sanmartin Nancy, Janvier Frédéric, Chianea Denis, Fagot Thierry, Renard Christophe, Vest Philippe

机构信息

Service de biochinie, Hôpital d'instruction des armées Percy, Clamart.

出版信息

Ann Biol Clin (Paris). 2011 Jan-Feb;69(1):121-5. doi: 10.1684/abc.2010.0508.

DOI:10.1684/abc.2010.0508

PMID:21464002

Abstract

We report the case of a patient with steroid-resistant nephrotic syndrome which is caused by a renal amyloidosis. This clinical case is characterized by intensity of clinicals and biologicals abnormalities and by its uncommun cause. We also review current data on the nephrotic syndrome as well as on the systemic amyloidosis and to evoke the indications of the immunoglobulin free-light-chains quantification in the diagnostic approach.

摘要

我们报告了一例由肾淀粉样变性引起的激素抵抗型肾病综合征患者的病例。该临床病例的特点是临床和生物学异常的严重程度以及其罕见的病因。我们还回顾了关于肾病综合征以及系统性淀粉样变性的当前数据，并探讨了在诊断方法中游离轻链定量的指征。