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新生儿的环状物。

Rings in the neonate.

作者信息

Hackett C B, McAleer M A, O'Donnell B F

机构信息

Department of Dermatology, The Children's University Hospital, Temple St, Dublin 1.

出版信息

Ir Med J. 2011 Feb;104(2):52-3.

Abstract

Neonatal lupus erythematosus (NLE) is an uncommon disease of the neonate. It is believed to be caused by the transplacental passage of maternal autoantibodies to the ribonucleoproteins (Ro/SSA, La/SSB or rarely U RNP) as these are almost invariably present in NLE sera. The most common clinical manifestations include cutaneous lupus lesions and congenital complete heart block. Hepatobiliary and haematologic abnormalities are reported less frequently. We describe a patient with cutaneous NLE to illustrate and raise awareness of the characteristic annular eruption of this condition. We also emphasize the need for thorough investigation for concomitant organ involvement and for maternal education regarding risk in future pregnancies.

摘要

新生儿红斑狼疮(NLE)是一种罕见的新生儿疾病。据信它是由母体自身抗体经胎盘传递至核糖核蛋白(Ro/SSA、La/SSB或极少情况下的U RNP)引起的,因为这些抗体几乎总是存在于NLE患者的血清中。最常见的临床表现包括皮肤狼疮病变和先天性完全性心脏传导阻滞。肝胆和血液学异常的报道较少。我们描述了一名皮肤型NLE患者,以说明并提高对这种疾病特征性环形皮疹的认识。我们还强调了对伴随器官受累进行全面检查以及对母亲进行关于未来妊娠风险教育的必要性。

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