Seizer P, Fateh-Moghadam S, Gawaz M, Bocksch W
Abteilung für Kardiologie und Kreislauferkrankungen, Medizinische Klinik, Universitätsklinikum Tübingen, Germany.
Dtsch Med Wochenschr. 2011 Apr;136(15):781. doi: 10.1055/s-0030-1247623. Epub 2011 Apr 5.
We report on a 42-year-old patient who presented with acute chest pain which occurred during defaecation. History revealed no cardiovascular risk factors.
ECG and laboratory testing showed an non-ST-elevation myocardial infarction (NSTEMI).
DIAGNOSIS, TREATMENT AND COURSE: Coronary angiography revealed an embolic occlusion of the ramus intermedius. As origin of the embolus a deep vein thrombosis and a persistent foramen ovale (PFO) was diagnosed. We occluded the PFO with an Amplatz occluder. Because of the traumatic deep vein thrombosis phenprocoumon and clopdiogrel were given for 6 months.
Patients with no cardiovascular risk profile, who present with typical chest pain, an embolic cause is an important differential diagnosis. Especially history is very helpful for the correct diagnosis. Interventional occlusion of PFO is a simple and safe approach for patients with symptomatic PFO regarding no permanent antithrombotic medication.
我们报告一例42岁患者,其在排便时出现急性胸痛。病史显示无心血管危险因素。
心电图和实验室检查显示非ST段抬高型心肌梗死(NSTEMI)。
诊断、治疗与病程:冠状动脉造影显示中间支有栓塞性闭塞。诊断栓子来源为深静脉血栓形成和卵圆孔未闭(PFO)。我们用Amplatz封堵器封堵了PFO。由于存在创伤性深静脉血栓形成,给予苯丙香豆素和氯吡格雷治疗6个月。
对于无心血管危险因素且出现典型胸痛的患者,栓子来源是一个重要的鉴别诊断。尤其是病史对正确诊断非常有帮助。对于有症状的PFO患者,在无需长期抗血栓药物治疗的情况下,经皮封堵PFO是一种简单且安全的方法。