Center for Melanoma Research and Treatment and Department of Surgery, California Pacific Medical Center and Research Institute, San Francisco, California 94115, USA.
J Surg Oncol. 2011 May 1;103(6):639-41. doi: 10.1002/jso.21839.
Nodal status is the most important predictor in patients with solid cancer. In general, sentinel lymph node is the gateway to regional nodal metastasis and beyond. Biomarkers and gene profiles are being developed to stage and subgroup cancer patients more accurately for more effective personalized therapy.
淋巴结状态是实体瘤患者最重要的预测指标。一般来说,前哨淋巴结是区域淋巴结转移的门户。目前正在开发生物标志物和基因谱,以更准确地对癌症患者进行分期和亚组分类,从而提供更有效的个体化治疗。