Department of Genito-Urinary Oncology, Moffitt Cancer Center, Tampa, FL 33612, USA.
Urol Oncol. 2013 Jul;31(5):505-16. doi: 10.1016/j.urolonc.2011.02.020. Epub 2011 Apr 11.
Inguinal lymph node dissection (ILND) for the treatment of metastatic penile squamous cell carcinoma (SCC) has historically been associated with significant morbidity. This review addresses the surgical principles and techniques to decrease its perioperative morbidity, while optimizing its oncologic outcomes.
A review of the English scientific literature from 1966 to present was conducted using the PubMed search engine as well as of additional cited works not initially noted in the search using as keywords penile cancer, inguinal lymph node dissection, inguinal lymph node metastasis, morbidity, and complications.
The contemporary outcomes of ILND in the context of penile cancer have built on the significant contributions made by surgeons and scientists worldwide. In this review, we provide a comprehensive overview of the principles of ILND optimizing oncological outcomes, while minimizing its attributable morbidity. It is hoped this review will serve as a benchmark for clinicians to approach this often highly aggressive tumor phenotype.
ILND remains an important diagnostic and therapeutic procedure for patients with penile SCC, as contemporary ILND series have reported a decrease in its associated morbidity, with the potential for further treatment outcomes in years to come. ILND can in appropriately selected patients render them disease-free, thus justifying its associated morbidity.
腹股沟淋巴结清扫术（ILND）是治疗转移性阴茎鳞状细胞癌（SCC）的传统方法，但与显著的发病率相关。本综述旨在探讨降低围手术期发病率、优化肿瘤学结果的手术原则和技术。
使用 PubMed 搜索引擎对 1966 年至今的英文科学文献进行综述，并使用未在搜索中记录的其他引用文献作为关键词，如阴茎癌、腹股沟淋巴结清扫术、腹股沟淋巴结转移、发病率和并发症，以进一步搜索。
在阴茎癌背景下，ILND 的当代结果建立在全球外科医生和科学家的重要贡献基础上。在本综述中，我们全面概述了优化肿瘤学结果、同时将发病率降至最低的 ILND 原则。我们希望这篇综述能为临床医生提供一个基准，以处理这种通常具有高度侵袭性的肿瘤表型。
ILND 仍然是治疗阴茎 SCC 患者的重要诊断和治疗方法，因为当代 ILND 系列报告其相关发病率降低，未来几年可能有进一步的治疗结果。在适当选择的患者中，ILND 可使他们无疾病，从而证明其相关发病率是合理的。
