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老年患者行 SPARC 耻骨后尿道中段吊带术的长期手术结局更差。

Worse long-term surgical outcomes in elderly patients undergoing SPARC retropubic midurethral sling placement.

机构信息

Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, WA 98101, USA.

出版信息

BJU Int. 2011 Sep;108(5):708-12. doi: 10.1111/j.1464-410X.2010.09880.x. Epub 2011 Apr 12.

Abstract

OBJECTIVE

• The purpose of our study was to evaluate long-term clinical outcomes following placement of a retropubic mid-urethral sling in patients aged 70 and over and to compare outcomes with those of a younger cohort of patients.

MATERIALS AND METHODS

• Patients with stress urinary incontinence undergoing retropubic polypropylene sling (SPARC(TM) ) placement were entered into a prospective, institutional review board-approved database. • Patients with at least 12 months follow-up were sent postoperative questionnaires assessing outcomes. Results of these questionnaires were compared for patients aged 70 or older and those younger than 70 years.

RESULTS

• A total of 337 patients who underwent SPARC sling placement in an 8-year period were identified. Of these, 290 patients had a minimum of 12 months follow-up, and among these patients, 235 (81%) answered postoperative mailed questionnaires. Average follow-up was 45.2 months. • Thirty-seven patients were 70 or older, and 198 were younger than 70. The older group had significantly lower success (53.1% vs 83.6%) and dry (6.1% vs 35.3%) rates than the younger cohort. • Assessment of preoperative variables determined that the older cohort had significantly more vaginal deliveries and a higher percentage of patients who had undergone either hysterectomy, previous prolapse and/or incontinence surgery. • There was no significant difference in Valsalva leak-point pressure, percentage of patients with intrinsic sphincteric deficiency or type 0 stress urinary incontinence between the two groups.

CONCLUSIONS

• Experience at our Institution shows that there are clearly lower success rates in older patients undergoing a SPARC sling as compared with a younger cohort of patients. • Parity, hysterectomy and previous pelvic organ prolapse/anti-incontinence surgery may also play a role in the difference in outcomes.

摘要

目的

本研究旨在评估 70 岁及以上患者行耻骨后尿道中段吊带术(SPARC(TM))的长期临床疗效,并与年轻患者的结果进行比较。

材料与方法

患者因压力性尿失禁行耻骨后聚丙烯吊带(SPARC(TM))置入术,入组前瞻性机构审查委员会批准的数据库。至少随访 12 个月的患者会被发送术后问卷调查,以评估其结果。对 70 岁及以上和 70 岁以下的患者进行问卷调查结果比较。

结果

8 年内共 337 例患者行 SPARC 吊带置入术,其中 290 例患者有至少 12 个月的随访,其中 235 例(81%)患者术后通过邮件回答了问卷调查。平均随访时间为 45.2 个月。37 例患者年龄在 70 岁或以上,198 例年龄在 70 岁以下。老年组的成功率(53.1%比 83.6%)和干燥率(6.1%比 35.3%)明显低于年轻组。术前变量评估发现,老年组阴道分娩率明显较高,且有更多患者行子宫切除术、既往脱垂和/或尿失禁手术。两组患者的 Valsalva 漏尿点压力、固有括约肌缺陷患者比例或 0 型压力性尿失禁类型无显著差异。

结论

本机构经验表明,SPARC 吊带术治疗 70 岁以上患者的成功率明显低于年轻患者。产次、子宫切除术和既往盆腔器官脱垂/抗失禁手术可能也是导致两组患者结果差异的原因。

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