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Computational protein design, from single domain soluble proteins to membrane proteins.
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Better library design: data-driven protein engineering.
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Computational design of membrane proteins.
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Biomolecular engineering for nanobio/bionanotechnology.
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Computational strategies for the design of new enzymatic functions.
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Computational Enzyme Design: Advances, hurdles and possible ways forward.
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Computational approaches for rational design of proteins with novel functionalities.
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Protein design: toward functional metalloenzymes.
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A protein engineered to bind uranyl selectively and with femtomolar affinity.
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Optimizing scoring function of protein-nucleic acid interactions with both affinity and specificity.
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Programmable ligand detection system in plants through a synthetic signal transduction pathway.
PLoS One. 2011 Jan 25;6(1):e16292. doi: 10.1371/journal.pone.0016292.
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Generation of longer emission wavelength red fluorescent proteins using computationally designed libraries.
Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20257-62. doi: 10.1073/pnas.1013910107. Epub 2010 Nov 8.
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Engineering a protein-protein interface using a computationally designed library.
Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19296-301. doi: 10.1073/pnas.1006528107. Epub 2010 Oct 25.
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De novo design and molecular assembly of a transmembrane diporphyrin-binding protein complex.
J Am Chem Soc. 2010 Nov 10;132(44):15516-8. doi: 10.1021/ja107487b.
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Probing designability via a generalized model of helical bundle geometry.
J Mol Biol. 2011 Jan 28;405(4):1079-100. doi: 10.1016/j.jmb.2010.08.058. Epub 2010 Oct 7.
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Identification of interacting hot spots in the beta3 integrin stalk using comprehensive interface design.
J Biol Chem. 2010 Dec 3;285(49):38658-65. doi: 10.1074/jbc.M110.170670. Epub 2010 Oct 7.
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Structure-based prediction of the peptide sequence space recognized by natural and synthetic PDZ domains.
J Mol Biol. 2010 Sep 17;402(2):460-74. doi: 10.1016/j.jmb.2010.07.032. Epub 2010 Jul 21.
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Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.
Science. 2010 Jul 16;329(5989):309-13. doi: 10.1126/science.1190239.
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A synthetic coiled-coil interactome provides heterospecific modules for molecular engineering.
J Am Chem Soc. 2010 May 5;132(17):6025-31. doi: 10.1021/ja907617a.
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Origins of catalysis by computationally designed retroaldolase enzymes.
Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4937-42. doi: 10.1073/pnas.0913638107. Epub 2010 Mar 1.

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