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Aldosterone receptors are involved in the mediation of the memory-enhancing effects of piracetam.

作者信息

Mondadori C, Häusler A

机构信息

Pharmaceutical Research Department, CIBA-GEIGY Limited, Basel, Switzerland.

出版信息

Brain Res. 1990 Aug 6;524(2):203-7. doi: 10.1016/0006-8993(90)90691-4.

Abstract

The blockade of the memory-enhancing effects of piracetam resulting from adrenalectomy can be abolished by substitution with either corticosterone or aldosterone. However, corticosterone substitution does not reinstate these effects if the aldosterone receptors are blocked by the aldosterone antagonist epoxymexrenon.

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