2009 年 H1N1 感染在疫苗可获得之前在 HIV 感染和未感染妇女中的血清学发生率。
Seroincidence of 2009 H1N1 infection in HIV-infected and HIV-uninfected women prior to vaccine availability.
机构信息
Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
出版信息
AIDS. 2011 Jun 1;25(9):1229-32. doi: 10.1097/QAD.0b013e3283471cf2.
Abstract
The 2009 H1N1 pandemic was a unique opportunity to investigate differences in influenza infection using serology by HIV status. Using serial serum specimens collected from 1 April to 30 September 2009 and the prior 2 years from Women's Interagency HIV study participants, there was no difference in serologic evidence of 2009 H1N1 infection among HIV-infected women with a CD4 cell count at least 350 cells/μl compared with HIV-uninfected women. Owing to evidence showing a greater risk of influenza-related complications, HIV-infected individuals should continue to be a priority group for vaccination.
摘要
2009 年 H1N1 大流行是一个独特的机会，可以通过血清学研究 HIV 感染者之间流感感染的差异。使用 Women's Interagency HIV study 参与者在 2009 年 4 月 1 日至 9 月 30 日期间收集的系列血清样本，以及前 2 年的数据，与未感染 HIV 的女性相比，CD4 细胞计数至少为 350 个/μl 的 HIV 感染者中，血清学证据表明其感染 2009 年 H1N1 的情况没有差异。由于有证据表明 HIV 感染者患与流感相关的并发症的风险更高，因此 HIV 感染者应继续成为疫苗接种的优先群体。
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