Bhandari Tina, Brown Erin
Department of Emergency Medicine, PGY-3, University of Toronto, Sunnybrook Hospital, Toronto, Ontario, Canada.
Ann Plast Surg. 2011 Aug;67(2):189-92. doi: 10.1097/SAP.0b013e3181f3e36e.
A case report of a rare proximal phalanx metastasis from a primary lung carcinoma is described. The presenting symptom of the patient was pain in the proximal phalanx of the index finger. Radiographs at the time of presentation were unremarkable, and no diagnosis was provided. Because of increasing pain and eventual swelling, the patient presented for emergency assessment. Radiographs, less than 3 months after initial assessment, demonstrated a large lytic lesion within the proximal phalanx. Biopsy of the lesion documented a large cell malignancy consistent with a poorly differentiated adenocarcinoma. Subsequent investigations documented an occult lung neoplasm. The patient underwent palliative ray resection followed by the initiation of palliative chemotherapy for the primary carcinoma. A brief review of literature regarding acrometastases is provided and the potential benefit of early positron emission tomography scanning is discussed.
本文描述了一例罕见的原发性肺癌近端指骨转移病例报告。患者的主要症状是食指近端指骨疼痛。就诊时的X线片无明显异常,未作出诊断。由于疼痛加剧并最终出现肿胀,患者前来进行急诊评估。初次评估后不到3个月的X线片显示近端指骨内有一个大的溶骨性病变。病变活检显示为大细胞恶性肿瘤,符合低分化腺癌。后续检查发现了隐匿性肺肿瘤。患者接受了姑息性射线切除,随后开始对原发性癌进行姑息化疗。本文还简要回顾了有关肢端转移的文献,并讨论了早期正电子发射断层扫描的潜在益处。