Department of Radiology, Nottingham University Hospitals, United Kingdom.
AJR Am J Roentgenol. 2011 May;196(5):1156-9. doi: 10.2214/AJR.10.5719.
Baastrup disease is characterized by the development of abnormal contact between adjacent spinous processes. The clinical significance remains unresolved, a few studies showing Baastrup disease as a cause of back pain. The aim of this study was to establish the frequency of Baastrup disease in a large unselected cohort to determine whether it is part of the expected spectrum of degenerative changes in the aging spine.
The abdominopelvic CT scans of 1008 patients divided equally into seven age groups were retrospectively reviewed. Baastrup disease was judged present if there was close contact between adjacent spinous processes and if the apposing ends were sclerotic. The presence of other degenerative changes, such as disk degeneration, spondylolisthesis, and facet osteoarthritis, at affected levels also was noted.
Evidence of Baastrup disease was found in 413 patients (41.0%). A decade-on-decade increase in frequency was found with a peak of 81.3% among patients older than 80 years. As many as five levels were found to be affected in some patients (4.1% of 413), but in most patients (35.4%), one level was affected. Baastrup disease was most common at L4-L5. Associated degenerative changes were found at almost all affected levels (899/901).
Baastrup disease occurs with high frequency among the elderly. Our data show that it develops with increasing age and is part of the expected degenerative changes in the aging spine. Because of the nearly universal association with other degenerative changes, we urge caution before diagnosing Baastrup disease as the cause of back pain.
Baastrup 病的特征是相邻棘突之间出现异常接触。其临床意义尚不清楚,有一些研究表明 Baastrup 病是背痛的原因。本研究旨在建立在一个大的未选择队列中 Baastrup 病的频率,以确定它是否是老年脊柱退行性变化的预期范围的一部分。
回顾性分析了 1008 例患者的腹盆 CT 扫描,这些患者平均分为 7 个年龄组。如果相邻棘突之间存在紧密接触,并且接触端硬化,则判断存在 Baastrup 病。还注意到受影响水平的其他退行性变化,如椎间盘退变、脊椎滑脱和小关节骨关节炎的存在。
在 413 例患者(41.0%)中发现了 Baastrup 病的证据。随着年龄的增长,其频率呈十年一增的趋势,80 岁以上患者的发病率达到 81.3%。在一些患者中多达五个水平受到影响(413 例中的 4.1%),但在大多数患者(35.4%)中只有一个水平受到影响。Baastrup 病最常见于 L4-L5。几乎所有受影响的水平都发现了相关的退行性变化(901 例中的 899 例)。
Baastrup 病在老年人中发病率很高。我们的数据表明,它随着年龄的增长而发展,是老年脊柱退行性变化的预期变化之一。由于与其他退行性变化几乎普遍存在关联,因此在诊断 Baastrup 病为背痛的原因之前,我们应谨慎行事。