Cuadros J A, García J, Alós J I, González-Palacios R
Seccione de Microbiología, Hospital de Alcalá de Henares, Madrid.
Enferm Infecc Microbiol Clin. 1990 Aug-Sep;8(7):429-33.
During a period of one year all patients referred to the Dermatology department with the diagnosis of dermatophytosis were studied to determine the incidence. Etiology, and epidemiology of these infections in the northeast of Madrid. We have evaluated the sensitivity and specificity of the direct examination with 10% KOH with respect to the culture as well as the correlation between the clinical diagnosis and the result of the mycologic examination. The annual incidence was 8.4 cases per 10,000 inhabitants and the most frequent causal agents in a total number of 135 patients were Epidermophyton floccosum in 48 (35.5%), Microsporum canis in 36 (26.6%), Trichophyton mentagrophytes in 28 (20.7%) and Trichophyton rubrum in 12 (8.8%). In 5 patients there were simultaneous infection by two different agents. In a third part of the cases a previous contact with animals was reported. The direct examination had a specificity of 98% and a sensitivity of 83%. The diagnosis in the nonungual infections was confirmed in the 54% of the cases. The incidence of dermatophytosis in our geographical area is high. Due to the similarities with other diseases, the mycologic examination by microscopy or culture is essential.
在一年的时间里,对所有被皮肤科诊断为皮肤癣菌病的患者进行了研究,以确定马德里东北部这些感染的发病率、病因和流行病学情况。我们评估了10%氢氧化钾直接检查相对于培养的敏感性和特异性,以及临床诊断与真菌学检查结果之间的相关性。年发病率为每10000名居民8.4例,在总共135例患者中,最常见的致病因子为絮状表皮癣菌48例(35.5%)、犬小孢子菌36例(26.6%)、须癣毛癣菌28例(20.7%)和红色毛癣菌12例(8.8%)。5例患者同时同时两种不同病原体同时感染。在三分之一的病例中报告有先前与动物接触史。直接检查的特异性为98%,敏感性为83%。54%的病例中非甲癣感染的诊断得到证实。我们所在地理区域皮肤癣菌病的发病率很高。由于与其他疾病相似,显微镜检查或培养的真菌学检查至关重要。