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DPP-4 inhibitors: impact on glycemic control and cardiovascular risk factors.

作者信息

Dicker Dror

机构信息

Internal Medicine D and Obesity Clinic, Hasharon Hospital, Rabin Medical Center, Tel Aviv University, Tel Aviv, Israel.

出版信息

Diabetes Care. 2011 May;34 Suppl 2(Suppl 2):S276-8. doi: 10.2337/dc11-s229.

Abstract
摘要

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The myocardial infarct size-limiting effect of sitagliptin is PKA-dependent, whereas the protective effect of pioglitazone is partially dependent on PKA.
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The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice.
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Advances in therapy for type 2 diabetes: GLP-1 receptor agonists and DPP-4 inhibitors.
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Dipeptidyl-peptidase-IV inhibition augments postprandial lipid mobilization and oxidation in type 2 diabetic patients.
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Safety and tolerability of sitagliptin in patients with type 2 diabetes: a pooled analysis.
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