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含氟基团功能化发光的金属铱(III)配合物的三联吡啶配合物:光物理、蛋白质结合、生物缀合和细胞摄取性质。

Functionalization of luminescent cyclometalated iridium(III) polypyridine complexes with a fluorous moiety: photophysics, protein-binding, bioconjugation, and cellular uptake properties.

机构信息

Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, People's Republic of China.

出版信息

Chem Commun (Camb). 2011 Oct 14;47(38):10548-50. doi: 10.1039/c1cc11423a. Epub 2011 Apr 27.

Abstract

A new class of luminescent cyclometalated iridium(III) polypyridine fluorous complexes has been designed; the fluorous pendant not only plays an important role in the photophysical and biological properties of the complexes, but also allows the facile isolation of biomolecules labeled with these complexes with fluorous solid-phase extraction (FSPE).

摘要

一类新型的发光环金属铱(III)多吡啶氟代配合物已经被设计出来;氟代侧链不仅在配合物的光物理和生物性质中起着重要作用,而且还允许用氟固相萃取(FSPE)轻松分离标记有这些配合物的生物分子。

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