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香港弧菌引起的菌血症被误鉴定为洛菲不动杆菌:韩国首例报告。

Bacteremia caused by Laribacter hongkongensis misidentified as Acinetobacter lwoffii: report of the first case in Korea.

机构信息

Department of Internal Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.

出版信息

J Korean Med Sci. 2011 May;26(5):679-81. doi: 10.3346/jkms.2011.26.5.679. Epub 2011 Apr 21.

DOI:10.3346/jkms.2011.26.5.679
PMID:21532861
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3082122/
Abstract

Laribacter hongkongensis is an emerging pathogen in patients with community-acquired gastroenteritis and traveler's diarrhea. We herein report a case of L. hongkongensis infection in a 24-yr-old male with liver cirrhosis complicated by Wilson's disease. He was admitted to a hospital with only abdominal distension. On day 6 following admission, he complained of abdominal pain and his body temperature reached 38.6℃. The results of peritoneal fluid evaluation revealed a leukocyte count of 1,180/µL (polymorphonuclear leukocyte 74%). Growth on blood culture was identified as a gram-negative bacillus. The isolate was initially identified as Acinetobacter lwoffii by conventional identification methods in the clinical microbiology laboratory, but was later identified as L. hongkongensis on the basis of molecular identification. The patient was successfully treated with cefotaxime. To the best of our knowledge, this case is the first report of hospital-acquired L. hongkongensis bacteremia with neutrophilic ascites.

摘要

香港阿克曼菌是一种引起社区获得性胃肠炎和旅行者腹泻的新兴病原体。本研究报告了 1 例 24 岁合并肝硬变、Wilson 病的男性患者感染香港阿克曼菌。患者因腹胀入住医院,入院第 6 天出现腹痛,体温达 38.6℃。腹腔液检查结果显示白细胞计数为 1180/µL(中性粒细胞 74%)。血培养生长出革兰阴性杆菌。临床微生物实验室的常规鉴定方法最初将分离株鉴定为鲁氏不动杆菌,但后来基于分子鉴定将其鉴定为香港阿克曼菌。该患者经头孢噻肟治疗后痊愈。据我们所知,这是首例中性粒细胞性腹水的医院获得性香港阿克曼菌菌血症的报告。

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J Korean Med Sci. 2010 Nov;25(11):1665-8. doi: 10.3346/jkms.2010.25.11.1665. Epub 2010 Oct 26.
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The complete genome and proteome of Laribacter hongkongensis reveal potential mechanisms for adaptations to different temperatures and habitats.香港利比菌的全基因组和蛋白质组揭示了其适应不同温度和栖息地的潜在机制。
PLoS Genet. 2009 Mar;5(3):e1000416. doi: 10.1371/journal.pgen.1000416. Epub 2009 Mar 13.
3
Susceptibility patterns of clinical and fish isolates of Laribacter hongkongensis: comparison of the Etest, disc diffusion and broth microdilution methods.
革兰氏阴性非发酵菌的鉴定:能有多难?
PLoS Negl Trop Dis. 2019 Sep 30;13(9):e0007729. doi: 10.1371/journal.pntd.0007729. eCollection 2019 Sep.
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Malate-Dependent Carbon Utilization Enhances Central Metabolism and Contributes to Biological Fitness of via CRP Regulation.依赖苹果酸的碳利用通过CRP调节增强中心代谢并有助于其生物学适应性。
Front Microbiol. 2019 Aug 28;10:1991. doi: 10.3389/fmicb.2019.01991. eCollection 2019.
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Transcriptomic Analysis of Laribacter hongkongensis Reveals Adaptive Response Coupled with Temperature.香港拉氏杆菌的转录组分析揭示了与温度相关的适应性反应。
PLoS One. 2017 Jan 13;12(1):e0169998. doi: 10.1371/journal.pone.0169998. eCollection 2017.
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A novel MLST sequence type discovered in the first fatal case of Laribacter hongkongensis bacteremia clusters with the sequence types of other human isolates.在首例香港拉氏杆菌菌血症致死病例中发现的一种新型多位点序列分型与其他人类分离株的序列分型聚类。
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