2 型糖尿病患者口腔表现及相关因素的临床研究。
Clinical study of the oral manifestations and related factors in type 2 diabetics patients.
机构信息
Public Health Secretariat, RN State.
出版信息
Braz J Otorhinolaryngol. 2011 Mar-Apr;77(2):145-52. doi: 10.1590/s1808-86942011000200002.
UNLABELLED
Diabetes Mellitus (DM) is reported with and associated to oral alterations, with conflicting results. The aim of this study was to identify the prevalence of oral soft tissue alterations in type 2 diabetes mellitus patients.
MATERIAL AND METHODS
Socioeconomic variables, gender, heredity, capillary glucose control and local factors (prosthesis, dry mouth sensation) were analyzed in 196 diabetic and non-diabetic patients enrolled in HIPERDIA, at 41 Health units of Natal, Brazil.
STUDY DESIGN
A case study.
RESULTS
The last blood glucose mean was 177.0 mg/dl for diabetics and 89.46 mg/dl for non-diabetics. Mean capillary blood glucose was elevated in diabetics (215.95 mg/dl); it was 102.31 mg/dl in non-diabetics. The family history confirmed the heredity nature of the disease in 68.8% of diabetic patients (n = 66) (p < 0.001); salivary flow was 49% (n = 47) in diabetics, and 34% (n = 34) in non-diabetics. Candidiasis was present in 30.5% of diabetic patients (n=29) and 36% of non-diabetics (n=36). Both groups had lesions in the palate - 81.4% (n = 35) in diabetics, and 71.1% in non-diabetics (n = 27) (p = 0.68).
CONCLUSION
The alterations are not related to diabetes and are present independently of having or not type 2 Diabetes Mellitus.
目的
本研究旨在确定 2 型糖尿病患者口腔软组织改变的患病率。
材料和方法
在巴西纳塔尔的 41 个卫生单位，对 HIPERDIA 中纳入的 196 例糖尿病和非糖尿病患者进行社会经济变量、性别、遗传、毛细血管血糖控制和局部因素（义齿、口干感）分析。
研究设计
病例研究。
结果
糖尿病患者的最后一次平均血糖为 177.0mg/dl，非糖尿病患者为 89.46mg/dl。糖尿病患者的毛细血管血糖平均值升高（215.95mg/dl）；非糖尿病患者为 102.31mg/dl。家族史证实了 68.8%（n=66）糖尿病患者（p<0.001）的疾病遗传性；糖尿病患者的唾液流率为 49%（n=47），非糖尿病患者为 34%（n=34）。糖尿病患者中念珠菌病的发生率为 30.5%（n=29），非糖尿病患者为 36%（n=36）。两组患者的上颚均有病变-糖尿病患者为 81.4%（n=35），非糖尿病患者为 71.1%（n=27）（p=0.68）。
结论
这些改变与糖尿病无关，且独立于是否患有 2 型糖尿病。
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