Herd M K, Woods M, Anand R, Habib A, Brennan P A
Maxillofacial Unit, Queen Alexandra Hospital, Portsmouth PO6 3LY, UK.
Br J Oral Maxillofac Surg. 2012 Jun;50(4):309-13. doi: 10.1016/j.bjoms.2011.03.263. Epub 2011 May 5.
Lymphoma commonly presents as a painless enlarging lump in the neck. With the establishment of the neck lump one-stop clinic, patients can be assessed promptly. Historically an open node biopsy specimen was required for definitive diagnosis, but in the last few years, many clinicians have advocated use of image-guided core biopsies, and some specialist centres monitor patients with fine needle aspiration cytology (FNAC) combined with other diagnostic techniques such as flow cytometry. In this article, we present current published papers on the management of suspected lymphoma in a patient who presents with a neck mass. We discuss the role of FNAC, core biopsy, open node biopsy, and imaging in the diagnosis of lymphoma before the patient is referred to the oncologist.
淋巴瘤通常表现为颈部无痛性肿大的肿块。随着颈部肿块一站式诊所的设立,患者能够得到及时评估。过去,明确诊断需要开放淋巴结活检标本,但在过去几年里,许多临床医生主张使用影像引导下的粗针活检,一些专科中心采用细针穿刺抽吸细胞学检查(FNAC)并结合其他诊断技术(如流式细胞术)对患者进行监测。在本文中,我们展示了目前已发表的关于颈部肿块患者疑似淋巴瘤管理的论文。在患者转诊至肿瘤学家之前,我们讨论了FNAC、粗针活检、开放淋巴结活检和影像学检查在淋巴瘤诊断中的作用。